The simple monomeric nature of GPCRs was deduced from simple mass-action type ligand-binding data, from the lack of cooperativity in signal transduction and from simple concentration-response ...

This study presents valuable findings by demonstrating that specific GPCR subtypes induce distinct extracellular vesicle miRNA signatures, highlighting a potential novel mechanism for intercellular ...

Ryuji Morizane, MD, Ph.D., of the Department of Medicine at Massachusetts General Hospital, is the senior/corresponding ...