In 1995 Stanford researchers published a seminal paper in the journal Science (“Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray”) introducing the first ...

Gene expression microarrays have been used in numerous applications, including identifying novel genes associated with certain cancers, classifying tumors, and predicting patient outcome.

Two of the critical issues that arise when examining DNA microarray data are (1) determination of which genes best discriminate among the different types of tissue, and (2) characterization of ...

ABSTRACT: Aberrant gene expression is critical for tumor initiation and progression. However, we lack a comprehensive understanding of all genes that are aberrantly expressed in human cancer. Recently ...

The mRNA is then used in the subsequent laboratory-based microarray experiment (Phase 2) from which gene expression is measured and ultimately analyzed. We show that obtaining a valid test for the ...

A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play powerful roles in regulating gene expression.