Gene expression and regulation describes the process by which information encoded in an organism's DNA directs the synthesis of end products, RNA or protein. The articles in this Subject space ...

A new study has found that ORC plays a broad, unexpected role in regulating human cell gene expression and chromatin ...

The accuracy of spatial gene expression profiles generated by probe-based in situ spatially-resolved transcriptomic technologies depends on the specificity with which probes bind to their intended ...

DNA Methylation Market OverviewDNA methylation is a biological process in which methyl groups (CH3) are added to the DNA ...

While the process via which different types of neurons are produced, also known as neurogenesis, has been the focus of ...

New research from the Wisconsin Institute for Discovery is tackling a complex packing problem. Thanks to the development of a powerful new computational tool introduced in a study published earlier ...

RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions ...

A zebrafish Cas9 knock-in model enables lineage-specific gene disruption to uncover genetic dependencies in development and disease.

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...