Here, by incorporating ligand-responsive self-cleaving catalytic RNAs (aptazymes) into guide RNAs, we developed a set of aptazyme-embedded guide RNAs that enable small molecule-controlled nuclease ...

The researchers implemented a guide RNA gene circuit capable of decision-making based on inputs, similar to a Boolean logic gate, which is one of the fundamental representations of input-output ...

Researchers have used guide RNAs to improve the adenine base editing (ABE) system, used by scientists to alter genetic codes in animal models of disease.

To learn more about Gene Editing watch “Webinar: CRISPR-Cas9 Gene Editing with Synthetic RNA – from start to finish!” Attendees will learn: the importance of a thorough and accurate guide RNA ...

The glycoRNAs derive from the RNA molecules within cells, but how they reach the cell surface is still a mystery. The investigators suggested that RNAs that are located inside of cells might be ...

Recently, researchers have transformed guide RNAs, which direct enzymes, into a smart RNA capable of controlling networks in response to various signals.

This scalable method to simultaneously capture and analyze guide RNAs, together with their effect on the transcriptome, is enabled on the 10x Genomics single-cell gene-expression solution with future ...

Recently, researchers have transformed guide RNAs, which direct enzymes, into a smart RNA capable of controlling networks in response to various signals.

New RNA editing technology may provide a simpler way to repair disease-causing mutations in RNA without compromising precision or efficiency.

Current CRISPR guide RNAs are designed based on European reference genomes, leading to false-negative results in cells from people with African ancestry.

Origin of life researchers figure out how to build bigger RNAs Pre-biochemistry can link small building blocks into bigger molecules.