We conclude that brain states are shaped by local circuit mechanisms, large-scale connectivity and neuromodulation. A unified multiscale theory of cortical dynamics is relevant not only for ...

Years ago, an audacious Fields medalist outlined a sweeping program that, he claimed, could be used to resolve a major ...

This correspondence between brain state and brain responsiveness (statedependent responses) is outlined at different scales from the cellular and circuit level, to the mesoscale and macroscale level.

Bright light reduces feeding and weight gain in mice by activating a specific retina-to-brain pathway that signals through the visual thalamus to inhibit appetite-regulating neurons in the ...