Guido Reichstadter sits outside an office of the artificial intelligence company Anthropic on Howard Street in downtown San ...

The NFL has added a new twist this season with "rivalries" uniforms that eight different teams will don this year, and the ...

A passenger aboard a Muni light rail vehicle was stabbed late Monday night, and a suspect was still at large, police said.

The San Francisco 49ers just can’t help themselves. Last year, they missed the playoffs for the first time since 2020, ...

San Francisco 49ers general manager John Lynch has made some very wise decisions in his eight-year tenure with the team.

A person was hospitalized with life-threatening injuries on Wednesday afternoon after being stabbed in San Francisco.

San Francisco 49ers tight end George Kittle was designated to IR after suffering a hamstring injury in Week 1.

The San Francisco Chronicle first reported on DoorDash's drone delivery plans. Most of the testing would happen inside the ...

Four people were shot on Burke Avenue in San Francisco; police are investigating and a suspect was arrested outside the ...

More than 100 people attended a hastily-called rally in support of mass transit on Monday. The aim was to urge the governor ...

As police were investigating shootings that occurred in the India Basin neighborhood of San Francisco on Tuesday evening, ...

Lyft is piloting autonomous rides in Atlanta with a safety driver on board, a long-planned launch meant to help it better ...