BACKGROUND: Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells.

Atherosclerotic cardiovascular disease is a major health concern worldwide and requires effective preventive measures. Lp(a) (lipoprotein [a]) has recently garnered attention as an independent risk ...

Hypertension in pregnancy contributes substantially to maternal morbidity and mortality, persistent hypertension, and rehospitalization. Hypertensive disorders of pregnancy are also associated with a ...

Chin YH, Yaow CYL, Teoh SE, Foo MZQ, Luo N, Graves N, Ong MEH, Ho AFW. Long-term outcomes after out-of-hospital cardiac arrest: a systematic review and meta-analysis. Resuscitation. 2022;171:15–29.

Suboptimal vascular risk factor screening after pregnancy-related hypertension or diabetes is a missed opportunity for cardiovascular prevention. Multifaceted strategies to improve screening, ...

Dilated cardiomyopathy (DCM) appears to be diagnosed twice as often in male than in female patients. This could be attributed to underdiagnosis in female patients or sex differences in susceptibility.

The activation and polarization of T cells play a crucial role in atherosclerosis and dictate athero-inflammation. The epigenetic enzyme EZH2 (enhancer of zeste homolog 2) mediates the H3K27me3 ...

Department of Pharmacy and Institute of Inflammation, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital (X.H., Y.Z., Y.W., G.L.) Zhejiang Provincial Key Laboratory of Laboratory ...

The developmental diversity among smooth muscle cells (SMCs) plays a crucial role in segment-specific aortic diseases. However, traditional genetic approaches are inadequate for enabling in vivo ...

Despite proven efficacy and safety of direct oral anticoagulants (DOACs) over warfarin in patients with atrial fibrillation (AF), data on patients with AF and valvular heart disease remain scarce. We ...