Fred Warner has "full confidence" in the San Francisco 49ers' chances in Week 2 vs. the New Orleans Saints despite injuries.

San Francisco 49ers tight end George Kittle has now been placed on IR. He will miss at least the next four weeks, meaning the earliest he could return to the field is Sunday, October 12th, when the 49ers face the Tampa Bay Buccaneers. That's just over a month away. Hamstring injuries are the worst.

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Instead, the 49ers let him try his hardest to blow their season opener against the Seattle Seahawks on Sunday. While one might be tempted to call such a decision inexplicable, it actually make perfect sense in the broader context of the Kyle Shanahan and John Lynch era.

Coach Kyle Shanahan told reporters on Wednesday that Purdy is a " long shot " to play in Week 2 vs. the New Orleans Saints due to toe and left shoulder injuries. Backup Mac Jones is line to start for San Francisco this week -- and, potentially, for multiple weeks.

The San Francisco 49ers earned a road win in Week 1, and they'll stay on the road for Week 2. Here's how to tell if the game will be on TV near you.

The San Francisco 49ers have kicked off their season with a win against the Seattle Seahawks, overcoming injuries and special teams blunders

Tight end George Kittle will miss at least the 49ers’ next four games on Injured Reserve, and Eddy Piñeiro has replaced kicker Jake Moody.

A handful of key roster moves for the San Francisco 49ers were made official ahead of Week 2 practices beginning.

Even with the low expectations of a rookie debut, it is hard to come away from Alfred Collins' first start with the 49ers and take any sort of positive.