The high court on Wednesday issued an opinion in one of the most highly anticipated decisions, delivering a setback for transgender rights. In a 6-3 ruling, the justices upheld a Tennessee law that restricts gender-affirming care for minors.

The conservative Supreme Court dealt a significant blow to transgender Americans on Wednesday, issuing a sweeping decision that may have implications beyond the medical care that was at center of one of the court’s highest-profile disputes this year.

The court's decision in the landmark U.S. v. Skrmetti case is expected to upend access to healthcare for trans youth.