Guido Reichstadter sits outside an office of the artificial intelligence company Anthropic on Howard Street in downtown San ...

The San Francisco 49ers just can’t help themselves. Last year, they missed the playoffs for the first time since 2020, ...

A passenger aboard a Muni light rail vehicle was stabbed late Monday night, and a suspect was still at large, police said.

The San Francisco Chronicle first reported on DoorDash's drone delivery plans. Most of the testing would happen inside the ...

A person was hospitalized with life-threatening injuries on Wednesday afternoon after being stabbed in San Francisco.

The NFL has added a new twist this season with "rivalries" uniforms that eight different teams will don this year, and the ...

SAN FRANCISCO (AP) — When Ryan Lee first played mahjong two years ago, he got hooked. He dug out sets of the classic Chinese ...

As police were investigating shootings that occurred in the India Basin neighborhood of San Francisco on Tuesday evening, ...

San Francisco 49ers tight end George Kittle was designated to IR after suffering a hamstring injury in Week 1.

San Francisco 49ers general manager John Lynch has made some very wise decisions in his eight-year tenure with the team.

Lyft is piloting autonomous rides in Atlanta with a safety driver on board, a long-planned launch meant to help it better ...

Redfin used a mortgage payment-to-income ratio to make its calculation. By that metric, homes cost about as much as they did ...