Publishes original research, insights and opinions on evidence-based research. Focuses on the tools, methods, and concepts that are central to practising evidence-based medicine.

From promise to practice: challenges and pitfalls in the evaluation of large language models for data extraction in evidence synthesis ...

Health literacy demands placed on patients and consumers are amplified in low-value care contexts and must be addressed as a system and organisational priority, argue Danielle Muscat and colleagues . ...

Healthcare delivery is being transformed by the rapid growth of data, advancements in artificial intelligence (AI) and other technologies. In healthcare, obtaining real-world data can be ...

Background Musculoskeletal knee pain is a large and costly problem, and meniscal tears make up a large proportion of diagnoses. ‘Special tests’ to diagnose torn menisci are often used in the physical ...

Objective This study evaluates whether Taiwan’s national oral cancer screening programme, implemented in 1999, has led to a ...

In 20 years of researching and teaching health risk communication methods, the most common question we get is: how should I communicate this [adverse event risk, survival probability, etc.] so that ...

A systematic review identifies, appraises and synthesises all the empirical evidence from studies that meet prespecified eligibility criteria to answer a specific research question. As part of the ...

Existing reporting checklists lack the specificity and comprehensiveness required to effectively guide the documentation of acupuncture case reports. Therefore, we developed a reporting guideline ...

When busy clinicians bump into a new treatment, they ask themselves 2 questions. Firstly, is it better than (“superior to”) what they are using now? Secondly, if it’s not superior, is it as good as ...

Choosing Wisely campaigns are clinician-led efforts to raise awareness and develop interventions to reduce low-value health care. At the core of Choosing Wisely campaigns are lists of recommendations, ...

The phenomenon of cancer overdiagnosis, the diagnosis of a malignant tumour that, without detection, would never lead to adverse health effects, has been reported for several cancer types in different ...