The effects of empagliflozin in patients with chronic kidney disease who are at risk for disease progression are not well understood. The EMPA-KIDNEY trial was designed to assess the effects of ...

Dr. Mallory C. Mandel (Pediatrics): A 16-year-old girl was admitted to this hospital because of abdominal pain. The patient had been in her usual state of health until 4 weeks before the current ...

Snakes are predators, and with exceptions (e.g., egg-eating snakes), they subdue their prey through constriction, aggressive biting, and chewing or by using venom. The mechanism of venom delivery ...

Aspiration pneumonia is best considered not as a distinct entity but as part of a continuum that also includes community- and hospital-acquired pneumonias. It is estimated that aspiration ...

Panel A shows second-degree frostbite of the foot after rewarming, with clear blisters and pink toes. Perfusion was detected in the toes. Thrombolysis was not advised, and the patient did well ...

We and others identified retinoblastoma features that suggested that the tumors originate in long- and medium-wavelength cone precursors, and we discovered features of these cone precursors that ...

Adipose tissue is an underappreciated and misunderstood organ. Capable of more than doubling in mass and then returning to baseline, 1 white adipose tissue (WAT) continues to play an essential ...

Neutrophils constitute the main infiltrating cell type in Behçet’s syndrome lesions. By producing excessive levels of reactive oxygen species and releasing neutrophil extracellular traps ...

Among women with epilepsy, studies regarding changes in seizure frequency during pregnancy have been limited by the lack of an appropriate nonpregnant comparator group to provide data on the ...

This review article presents two true-life clinical vignettes that illustrate how digital health technology can aid providers caring for patients with epilepsy. Specific information that would ...

Intravenous fluids are recommended for the treatment of patients who are in septic shock, but higher fluid volumes have been associated with harm in patients who are in the intensive care unit (ICU).

This article reviews the progress made during the past decade in elucidating the pathophysiological mechanisms of hereditary angioedema and the subsequent development of targeted treatments for ...