Weak Acids, Bases, and pKa in Biochemical Systems
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Weak Acids, Bases, and pKa in Biochemical Systems
In biological systems, essential biochemicals such as carboxyls, amines, and phosphates act as weak acids and bases that only partially dissociate, unlike strong acids that dissociate completely. The dissociation constant and acid strength of these molecules are described by pKa, which is the negative logarithm of Ka. A lower pKa value ...
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